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61.
An association is described between women with lupus anticoagulant and abnormal prenatal serum screening results. Three cases of positive second-trimester serum screening for Down syndrome, with karyotypically normal fetuses, in women demonstrated to have lupus anticoagulant are presented. Serum screening positivity was principally due to a disproportionately elevated maternal serum human chorionic gonadotrophin (hCG) level. In each case, early, severe intrauterine growth restriction was documented, with only one fetus surviving the neonatal period. As maternal lupus anticoagulant may have a profoundly adverse effect on the course of pregnancy, we suggest that an elevated hCG level on prenatal screening prompt consideration of maternal lupus anticoagulant testing if ultrasonography demonstrates an otherwise normal singleton gestation and the fetal karyotype is normal.  相似文献   
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Ohne Zusammenfassung Verantwortliche Herausgeber: Jan Schwarzbauer · Peter Heininger · Evelyn Claus
Henner Hollert (Corresponding author)Email:
Evelyn ClausEmail:
Peter HeiningerEmail:
Jan SchwarzbauerEmail:
  相似文献   
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Despite the fact that adverse health effects of asbestos have been known since shortly after the turn of the century,1 there has been little progress in techniques for determining the mineral in the airborne state. This absence of sampling and analysis methods appears to derive from two main sources: (1) In the environments of the asbestos using industries, asbestos concentrations tend to be high relative to other particulate species, and especially compared with other fibrous species, making estimation of concentration by microscopy relatively easy. (2) The term "asbestos" describes a crystal habit, not a chemical compound; therefore there is no unique chemical property of asbestos that can be used as the basis for its measurement. Interestingly, there appears to be no basis for distinguishing the health effects of one type of asbestos over another;2 the physiological response seems more dependent on crystal habit than on composition.  相似文献   
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Scientists have shown that the practice of factory farming is an increasingly urgent danger to human health, the environment, and nonhuman animal welfare. For all these reasons, moral agents must consider alternatives. Vegetarian food production, humane food animal farming, and in-vitro meat production are all explored from a variety of ethical perspectives, especially utilitarian and rights-based viewpoints, all in the light of current U.S. and European initiatives in the public and private sectors. It is concluded that vegetarianism and potentially in-vitro meat production are the best-justified options.  相似文献   
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Guo  Xianwei  Su  Wanying  Li  Ning  Song  Qiuxia  Wang  Hao  Liang  Qiwei  Li  Yaru  Lowe  Scott  Bentley  Rachel  Zhou  Zhen  Song  Evelyn J.  Cheng  Ce  Zhou  Qin  Sun  Chenyu 《Environmental science and pollution research international》2022,29(45):67483-67503
Environmental Science and Pollution Research - Amounting epidemiological evidence has shown detrimental effects of heavy metals on a wide range of diseases. However, the effect of heavy metal...  相似文献   
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David Sztybel has argued that defenders of the moralsignificance of animals have not made an effective case against theirenemy: anthropocentrism. He maintains that they have refuted only``straw' versions of that view. Sztybel opposes anthropocentrism, butis convinced that it is a much more difficult view to defeat than hasbeen thought. He develops the strongest argument possible for``Obligatory Anthropocentrism' (OA), defending it against manyobjections. He also holds that OA does not have unpalatable implicationsfor the treatment of average, below average, and mentally challengedhumans. While I agree that Sztybel has done an admirable job ofdefending anthropocentrism, indeed a better job than theanthropocentrists themselves, I argue that his case for OA is subtly butfatally flawed. I also argue that OA does not dodge two very seriouscriticisms concerning its implications for the treatment of certainhuman beings: the charge of invidious perfectionism and the argumentfrom marginal cases. I conclude that the strongest version ofanthropocentrism is, in fact, not strong enough.  相似文献   
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